When I am talking about protein structure prediction, then I am considering the prediction of tertiary structure of protein only. We can talk about secondary and Quaternary protein structure prediction later
Protein 3D Structure Prediction Tutorial : Part-I
Purposes of Modeling
Explaining phenotype of existing mutations
Designing mutants to disrupt or alter specific
functions
Prediction about function
Drug design
Hypothesis generation
Common Terms Used in Protein Structure Modelling
Methods of Protein Structure Modelling
- Ab initioprotein modelling - prediction based on physical principles rather than on any previously solved structures. Read more
- Comparative protein modeling - model prediction using previously solved structures as a template.
- Homology Modeling : based on assumption that two homologous proteins will share very similar structures. Read more
- Protein threading : Utilize to predict structure of those protein which have the same fold as proteins of known structures, but do not have homologous proteins with known structure. Read more
Part-III: Video Tutorial for Protein 3D Structure Prediction
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